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Supplementary Figure S9: from (R)-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in IDH-Mutant Cancers

Authors :
Julie-Aurore Losman
Peppi Koivunen
Lucy A. Godley
Cihangir Duy
Hai Yan
Samuel K. McBrayer
Harley I. Kornblum
Keith L. Ligon
John G. Doench
Ryan Looper
Michael M. Levitt
Bill H. Diplas
Betty Rouaisnel
Bofu Huang
Manna Ahmed
John Z. Cao
Matti Myllykoski
Kathryn Gunn
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Genomic regions marked by increased trimethyl-H3K4 are enriched in IDH1-mutant glioma MCTS lines when compared to IDH1-wild-type MCTS lines.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....78da4c2364db24a8c9e614352057b9be
Full Text :
https://doi.org/10.1158/2159-8290.22726158