Lymphocyte‐to‐monocyte ratio combined with CA19‐9 for predicting postoperative recurrence of colorectal cancer in patients with diabetes

Objective To investigate the significance of lymphocyte‐to‐monocyte ratio (LMR) combined with carbohydrate antigen (CA) 19‐9 for predicting postoperative recurrence of colorectal cancer (CRC) in patients with type II diabetes. Methods We conducted a retrospective analysis of 106 postoperative patients with stage II–III CRC and with type II diabetes. Their clinical indexes such as LMR and CA19‐9 were collected, and the patients were followed up for 5 years. Results The CA19‐9 level was 119.7 U/ml at baseline in the relapsed group, while this was 24.81 U/ml in non‐relapsed group (p = 0.001). On the contrary, the LMR level was 5.10 and 2.57 for non‐relapsed and relapsed group (p
In the present study, a total of 106 patients with CRC and type II diabetes before surgery were included in the analysis, the median follow‐up was 60 months, and 38 had a disease recurrence. We found that both LMR and CA19‐9 are significantly related to prognosis, and the combination of the above two is expected to become a new index for predicting postoperative recurrence of CRC in patients with diabetes.