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Supplementary Figures from MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin

Authors :
Karen L. MacKenzie
Jamie I. Fletcher
Giovanni Perini
Murray D. Norris
Preethi H. Gunaratne
Michelle Haber
Wendy B. London
Hilda A. Pickett
Georg von Jonquieres
Claudia L. Flemming
Amanda J. Russell
Jayne Murray
Chen Yang
Stefania Purgato
Cheng Fei Kong
Bing Liu
Michelle F. Maritz
Sieu L. Tran
Rosemary O'Brien
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Supporting data; Supplementary Figure 1:Correlation analysis of DKC1 mRNA and dyskerin protein quantity in neuroblastoma cell lines Supplementary Figure 2:Correlation analysis of telomerase activity gene expression in neuroblastoma cells Supplementary Figure 3:Correlation analysis of TERT and MYC gene expression in neuroblastoma tumor samples Supplementary Figure 4:High DKC1 expression is a marker of poor prognosis in neuroblastoma Supplementary Figure 5:Analysis of TERT expression in neuroblastoma tumor samples Supplementary Figure 7: Upregulation of p21cip1 in NB69, but not SK-N-BE(2) cells following down regulation of dyskerin Supplementary Figure 8: Cell cycle and viability following downregulation of dyskerin

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....794cfbdb3bcad0e4b5ee232834ca8996
Full Text :
https://doi.org/10.1158/0008-5472.22410275.v1