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A 49-year-old man with ischemic cardiomyopathy and persistent hemoptysis for eighteen months

Authors :
Alexis, Aiman
Santu, Saha
Woon H, Chong
Biplab K, Saha
Source :
The American Journal of the Medical Sciences. 364:111-117
Publication Year :
2022
Publisher :
Elsevier BV, 2022.

Abstract

Idiopathic pulmonary hemosiderosis (IPH) is a rare cause of recurrent episodes of diffuse alveolar hemorrhage (DAH). IPH commonly manifests with hemoptysis, radiologic chest infiltrates and anemia. The etiology of IPH is unknown, but an immunologic mechanism is widely speculated. The definitive diagnosis of IPH requires a thorough exclusion of other causes of DAH, such as infections, inflammation, malignancy, cardiac diseases, drug and toxin exposure, and medications. Due to the rarity of the disease, a diagnosis is often delayed by years. We present the case of a 49-year-old man with ischemic cardiomyopathy who presented with hemoptysis for eighteen months. Serologic workup was negative for vasculitides and autoimmune diseases. Bronchoscopy revealed DAH. A surgical lung biopsy showed 'bland pulmonary hemorrhage.' A right heart catheterization ruled out cardiac causes of DAH. The patient was diagnosed with IPH and started on systemic corticosteroids with rapid improvement of hemoptysis.

Details

ISSN :
00029629
Volume :
364
Database :
OpenAIRE
Journal :
The American Journal of the Medical Sciences
Accession number :
edsair.doi.dedup.....7987b423bb348659083dfdbcb941ad40
Full Text :
https://doi.org/10.1016/j.amjms.2021.10.030