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Personality profile and health-related quality of life in adults with previous continuous spike-waves during slow sleep syndrome
- Source :
- Brain and Development. 41:522-530
- Publication Year :
- 2019
- Publisher :
- Elsevier BV, 2019.
-
Abstract
- Introduction Epilepsy with continuous spike-waves during slow sleep syndrome (CSWSS) is characterized by various seizure types, a characteristic EEG pattern and neuropsychological disorders. The main purpose of this study was to evaluate the long-term outcome of CSWSS occurred in childhood and to evaluate the variables that could influence the quality of social adaptation and the personality profile. Material and methods This is a prospective study on 24 young adults with previous CSWSS (median age 24.5 yrs) who were enrolled between January and July 2011 at the G. Gaslini Children’s Hospital, Genoa, Italy. Patients were divided into two groups: twelve with previous spike-wave index (SWI > 85%) defined as typical CSWSS (T-CSWSS) and twelve with previous SWI = 50–85% defined as atypical CSWSS (A-CSWSS). All the subjects were submitted to Minnesota Multiphasic Personality Inventory-2 (MMPI-2), Psychological General Well-Being Index (PGWBI), and to a structured interview. Results A correlation was observed with the severity of EEG abnormalities expressed by the SWI and outcome. The T-CSWSS group showed a significantly lower perceived well-being. Similarly in the T-CSWSS group the percentage of MMPI-2 clinical scales with T-scores ≥65 was higher than in the A-CSWSS group. Finally, a significant lower schooling in the T-CSWSS group was observed. Conclusion There seem to be two forms of the same disease, with similar onset and clinical evolution but a different outcome regarding the social and psychological conditions. The outcome of the social adaptation and of the personality consciousness was related with the severity of the EEG abnormalities: more favorable in patients with less intense SWI activity (A-CSWSS) compared those with a more severe EEG impairment (T-CSWSS).
- Subjects :
- Adult
Male
Sleep Wake Disorders
Psychological General Well-Being Index (PGWBI)
Pediatrics
medicine.medical_specialty
Continuous Spike-Waves During Slow-Wave Sleep Syndrome (CSWSS)
media_common.quotation_subject
Spike-Wave Index (SWI)
Electroencephalography
Sleep, Slow-Wave
03 medical and health sciences
Epilepsy
0302 clinical medicine
Developmental Neuroscience
Minnesota Multiphasic Personality Inventory
Minnesota Multiphasic Personality Inventory-2 (MMPI-2)
Outcome
Young adult
Humans
Medicine
Personality
Prospective Studies
Prospective cohort study
media_common
medicine.diagnostic_test
business.industry
Neuropsychology
Syndrome
General Medicine
medicine.disease
Italy
Pediatrics, Perinatology and Child Health
Structured interview
Quality of Life
Female
Neurology (clinical)
Sleep
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 03877604
- Volume :
- 41
- Database :
- OpenAIRE
- Journal :
- Brain and Development
- Accession number :
- edsair.doi.dedup.....79b0b00e92b35bad06c6c77ac5ee33f6