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Contrast Harmonic Imaging of Canine Hepatic Tumors
- Source :
- Journal of Veterinary Medical Science. 68:433-438
- Publication Year :
- 2006
- Publisher :
- Japanese Society of Veterinary Science, 2006.
-
Abstract
- Six adult healthy Beagles were used to investigate the hepatic perfusion dynamics of Levovist, a contrast agent used in contrast harmonic imaging (CHI). In addition, 8 dogs with hepatocellular carcinoma (HCC) and 2 dogs with metastatic hepatic hemangiosarcoma (HSA) were used to characterize both the CHI findings with Levovist. In the Beagles, the start of intravenously injected Levovist into the aorta between the cranial mesenteric and renal arteries and the portal vein at the hepatic hilum were 5.47 +/- 1.52 sec and 16.03 +/- 3.39 sec, respectively. As a characteristic CHI finding in the 8 dogs with HCC, the early arterial phase showed a fine network of blood flow enhanced at the surrounding region and within the tumor in all the 8 dogs (100%), and the post vascular phase demonstrated a defect in the whole tumor and an enhancement of the surrounding hepatic tissues in 7 dogs (87.5%). In the 2 dogs with HSA, characteristic finding in which the early arterial and late vascular phases showed a rim contrast enhancement pattern, and the post vascular phase revealed that the whole tumor lacked contrast enhancement and the surrounding hepatic tissues was clearly enhanced. In dogs, the start of the early arterial and late vascular phases, and the characterizations of the CHI findings in HCC and HSA were suggested to be similar to those in humans. Therefore, CHI is thought to be useful for the diagnosis of HCC and metastatic hepatic HSA in dogs as well as in humans.
- Subjects :
- Male
Pathology
medicine.medical_specialty
Carcinoma, Hepatocellular
Hemangiosarcoma
Contrast Media
Hilum (biology)
Dogs
Polysaccharides
medicine.artery
Carcinoma
Animals
Medicine
Dog Diseases
Neoplasm Metastasis
Ultrasonography
Aorta
General Veterinary
business.industry
Liver Neoplasms
Blood flow
medicine.disease
Liver
Hepatocellular carcinoma
Female
Sarcoma
business
Perfusion
Subjects
Details
- ISSN :
- 13477439 and 09167250
- Volume :
- 68
- Database :
- OpenAIRE
- Journal :
- Journal of Veterinary Medical Science
- Accession number :
- edsair.doi.dedup.....79bfb64ace5463ea30097ef8a017aec1
- Full Text :
- https://doi.org/10.1292/jvms.68.433