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Exploring the gap between National Cholesterol Education Program guidelines and clinical practice in secondary care: results of a cross-sectional study involving over 10 000 patients followed in different specialty settings across Italy
- Source :
- Journal of cardiovascular medicine (Hagerstown, Md.). 9(9)
- Publication Year :
- 2008
-
Abstract
- OBJECTIVES To evaluate implementation of low-density lipoprotein cholesterol (LDL-C) control recommendations in secondary care and explore key points in the decisional workup. METHODS AND RESULTS In a nationwide survey of secondary-care outpatients (n=11,124), we studied prevalence/predictors of (1) LDL-C value availability; (2) ongoing treatment with statins; (3) achievement of US National Cholesterol Education Program III target LDL-C values. Agreement between US National Cholesterol Education Program III risk category and physicians' personal risk assessments was also studied. LDL-C values were available for 78% evaluable patients; 71% of the patients with dyslipidema were undergoing treatment with statins; 34% patients undergoing treatment had target LDL-C values. At regression analysis, non-availability of LDL-C values was predicted by absence of diabetes, presence of normotension, and advancing age; lack of statins treatment by female sex, diabetes, overweight and northern location (southern location predicted treatment); non-achievement of target LDL-C values by age, diabetes, attending a diabetic clinic, cigarette smoking, history of cardiovascular disease, and taking less than six pills per day. Physicians provided underestimates of patients' risk (39% high-risk patients were rated as intermediate-risk patients and a further 10% as low-risk patients). CONCLUSION Suboptimal prevention practice seems to be associated with various factors acting at different levels within the complex process running from individual risk-level ascertainment to LDL-C target achievement. Multicomponent interventions that target the different key steps need to be considered.
- Subjects :
- Male
medicine.medical_specialty
Cross-sectional study
Specialty
Disease
Overweight
Risk Factors
Diabetes mellitus
Internal medicine
medicine
Ambulatory Care
Humans
National Cholesterol Education Program
Aged
Dyslipidemias
business.industry
General Medicine
Cholesterol, LDL
Middle Aged
medicine.disease
Italy
Cardiovascular Diseases
Family medicine
Pill
Health Care Surveys
Practice Guidelines as Topic
lipids (amino acids, peptides, and proteins)
Female
Guideline Adherence
medicine.symptom
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Cardiology and Cardiovascular Medicine
business
Risk assessment
Subjects
Details
- ISSN :
- 15582027
- Volume :
- 9
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Journal of cardiovascular medicine (Hagerstown, Md.)
- Accession number :
- edsair.doi.dedup.....79f5f493f40bf2cb5d1245f98f1f0b2d