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Beta-defensin genes of the Colubridae snakes Phalotris mertensi, Thamnodynastes hypoconia, and T. strigatus
- Source :
- Toxicon. 146:124-128
- Publication Year :
- 2018
- Publisher :
- Elsevier BV, 2018.
-
Abstract
- β-Defensins are cationic antimicrobial peptides showing little sequence similarity but highly conserved tertiary structure stabilized by a six-cysteines-motif. Using a PCR approach, we described β-defensin sequences with two exons in three species of Colubridae snakes with high sequence similarity between them. The deduced amino acid sequence presented the characteristics of β-defensin family. The phylogenetic analysis using β-defensin coding sequences of different snakes grouped them in two main branches: genes organized in three or two exons.
- Subjects :
- 0301 basic medicine
beta-Defensins
integumentary system
Phylogenetic tree
Thamnodynastes hypoconia
Colubridae
Exons
respiratory system
Biology
Toxicology
biology.organism_classification
Protein tertiary structure
03 medical and health sciences
030104 developmental biology
Beta defensin
Evolutionary biology
Animals
Amino Acid Sequence
Gene
Peptide sequence
Phylogeny
Sequence (medicine)
Subjects
Details
- ISSN :
- 00410101
- Volume :
- 146
- Database :
- OpenAIRE
- Journal :
- Toxicon
- Accession number :
- edsair.doi.dedup.....7a3320554eb9da949f66b257b96ebb8b