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Insulin immuno-neutralization in fed chickens: effects on liver and mucle transcriptome

Authors :
Cédric Cabau
Dragan Milenkovic
Sonia Métayer-Coustard
Michel J. Duclos
Nicole Rideau
Christelle Hennequet-Antier
Michel Derouet
Anne Collin
Larry A. Cogburn
Tom E. Porter
Joëlle Dupont
Jean Simon
Christian Gespach
E. Cailleau-Audouin
Sabine Crochet
Sophie Tesseraud
Estelle Godet
ProdInra, Archive Ouverte
Unité de Recherches Avicoles (URA)
Institut National de la Recherche Agronomique (INRA)
Unité de Nutrition Humaine (UNH)
Institut National de la Recherche Agronomique (INRA)-Université d'Auvergne - Clermont-Ferrand I (UdA)-Clermont Université
U673
Institut National de la Santé et de la Recherche Médicale (INSERM)
Université Pierre et Marie Curie - Paris 6 (UPMC)
CHU Saint-Antoine [AP-HP]
Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)
University of Maryland [College Park]
University of Maryland System
Physiologie de la reproduction et des comportements [Nouzilly] (PRC)
Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur] (IFCE)-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS)
University of Delaware [Newark]
Recherches Avicoles (SRA)
Clermont Université-Université d'Auvergne - Clermont-Ferrand I (UdA)-Institut National de la Recherche Agronomique (INRA)
CHU Saint-Antoine [APHP]
Centre National de la Recherche Scientifique (CNRS)-Université de Tours-Institut Français du Cheval et de l'Equitation [Saumur]-Institut National de la Recherche Agronomique (INRA)
Université d'Auvergne - Clermont-Ferrand I (UdA)-Clermont Université-Institut National de la Recherche Agronomique (INRA)
Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours-Centre National de la Recherche Scientifique (CNRS)
Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS)
Source :
Physiological Genomics, Physiological Genomics, 2012, 44 (5), pp.283-292. ⟨10.1152/physiolgenomics.00057.2011⟩, Physiological Genomics, American Physiological Society, 2012, 44 (5), pp.283-292. ⟨10.1152/physiolgenomics.00057.2011⟩, Physiological Genomics 5 (44), 283-292. (2012)
Publication Year :
2012
Publisher :
HAL CCSD, 2012.

Abstract

Chickens mimic an insulin-resistance state by exhibiting several peculiarities with regard to plasma glucose level and its control by insulin. To gain insight into the role of insulin in the control of chicken transcriptome, liver and leg muscle transcriptomes were compared in fed controls and “diabetic” chickens, at 5 h after insulin immuno-neutralization, using 20.7K-chicken oligo-microarrays. At a level of false discovery rate

Subjects

Subjects :
muscle
Physiology
medicine.medical_treatment
Insulin Antibodies
gallus gallus
[SDV.GEN] Life Sciences [q-bio]/Genetics
Neutralization
Transcriptome
0302 clinical medicine
Insulin
2. Zero hunger
0303 health sciences
insuline
biology
GENETIQUE ANIMALE
foie
Reverse transcription polymerase chain reaction
Liver
metabolism
insulin responsive gene
diabete
gene expression
signaling pathway
Antibody
Signal transduction
Metabolic Networks and Pathways
medicine.medical_specialty
expression génique
poulet
030209 endocrinology & metabolism
03 medical and health sciences
Neutralization Tests
Diabetes mellitus
Internal medicine
Genetics
medicine
Animals
Muscle, Skeletal
métabolisme
030304 developmental biology
[SDV.GEN]Life Sciences [q-bio]/Genetics
Proteins
Metabolism
medicine.disease
Microarray Analysis
Animal Feed
Antibodies, Neutralizing
Endocrinology
Gene Expression Regulation
biology.protein
Chickens

Details

Language :
English
ISSN :
10948341 and 15312267
Database :
OpenAIRE
Journal :
Physiological Genomics, Physiological Genomics, 2012, 44 (5), pp.283-292. ⟨10.1152/physiolgenomics.00057.2011⟩, Physiological Genomics, American Physiological Society, 2012, 44 (5), pp.283-292. ⟨10.1152/physiolgenomics.00057.2011⟩, Physiological Genomics 5 (44), 283-292. (2012)
Accession number :
edsair.doi.dedup.....7a4812f0ae302f793d1a9a494077c43a
Full Text :
https://doi.org/10.1152/physiolgenomics.00057.2011
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