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The Expression of hnRNP A2/B1 in Benign and Malignant Lung Lesions and Its Early Diagnosis Value in NSCLC

Authors :
Wenchao Gu
Xiwen Gao
Linxun Wang
Guoping Deng
Jiaru Huang
Junxia Yang
Yuan Liu
Qun Liu
Hongyang Sang
Source :
Contrast mediamolecular imaging. 2022
Publication Year :
2022

Abstract

Lung cancer in its occurrence and development of different stages exist different biological behavior changes. This paper studies the expression of heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1 in benign and malignant lung lesions and its early diagnosis value of nonsmall-cell lung cancer (NSCLC), aiming to provide reference for the early diagnosis and therapy of NSCLC. Some lung surgery specimens are selected from January 2021 to March 2022. All cases received no radiotherapy and chemotherapy before surgery, including 90 sufferers with benign lung lesions as the contrast set. hnRNP A2/B1 expressions are measured for comparison. The experimental results show that for lung cancer sufferers, the positive expression of hnRNP A2/B1 in their malignant lesion tissue is notoriously higher than that in their benign lesion tissue, and hnRNP A2/B1 is differently expressed in different differentiation and in different stages.

Details

ISSN :
15554317
Volume :
2022
Database :
OpenAIRE
Journal :
Contrast mediamolecular imaging
Accession number :
edsair.doi.dedup.....7a74ac464d9a7247465e18db4d26f10b