Reduced urinary angiotensinogen excretion in preeclampsia

Authors :: Thomas J. Kuehl
Syeda H. Afroze
Roksana Akter
A.H.M. Zuberi Ashraf
Ahmed F. Pantho
Mohammad N. Uddin
Natalie S. Colόn
Source :: Pregnancy Hypertension. 27:1-5
Publication Year :: 2022
Publisher :: Elsevier BV, 2022.
Abstract: OBJECTIVE This study evaluated urinary angiotensinogen in preeclampsia. METHODS Normal pregnant (n = 57) and preeclamptic patients (n = 31); Normal pregnant (n = 10) and preeclamptic rats (n = 10) were studied. Urinary angiotensinogen and plasma angiotensin II were assayed by enzyme-linked immunosorbent assay (ELISA). RESULTS Urinary angiotensinogen in preeclampsia patients (2.0 ± 1.1 ng/mg creatinine) was suppressed (*p

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