A Population-Based Examination of the Surgical Outcomes for Patients with Esophageal Sarcoma

Esophageal sarcoma (ES) is a rare malignancy. The literature is limited to small case series and reports. This study used a population data set to study the characteristics, treatments, surgical outcomes, and prognostic factors for survival among ES patients. The study identified 178 ES cases (0.3 %) and 63,548 esophageal carcinoma (EC) cases (99.7 %) including adenocarcinoma and squamous cell carcinoma using the Surveillance, Epidemiology, and End Results (SEER) Registry (1973–2011). Characteristics and therapeutics were compared between ES and EC. Survival data were analyzed using Kaplan–Meier estimation. Uni- and multivariate Cox proportional hazard models determined predictors of 5-year overall survival (OS). Compared with the EC patients, the ES patients were more likely to be women, to have localized tumors, and to undergo surgery but less likely to receive radiation (p