Back to Search
Start Over
Wide spread of carbapenemase-producing bacterial isolates in a Nigerian environment
- Source :
- Journal of Global Antimicrobial Resistance, Vol 21, Iss, Pp 321-323 (2020)
- Publication Year :
- 2020
-
Abstract
- Objectives The presence of carbapenemase-producing bacterial isolates is found not only in hospital and community settings but also in the environment. Carbapenemase production may be related to acquired, usually plasmid-borne, β-lactamase genes or to chromosomal genes intrinsic to various species. The aim of this study was to evaluate the occurrence of such carbapenemase-producing bacterial isolates among environmental samples from Nigeria. Methods A total of 122 environmental samples were plated on carbapenem-containing media. A total of 259 isolates were recovered, among which 124 were carbapenemase-producers according to the results of the Rapidec® Carba NP test. Results The majority of isolates (n = 112) recovered corresponded to natural producers of carbapenemases, i.e. Stenotrophomonas maltophilia (n = 108), Burkholderia cepacia (n = 1), Shewanella sp. (n = 1), Sphingobacterium sp. (n = 1) and Chryseobacterium gleum (n = 1). Ten isolates (mainly Enterobacteriaceae and Acinetobacter baumannii) produced an acquired carbapenemase, most commonly of the NDM type. In addition, two Pseudomonas otitidis isolates were identified as producing the Ambler class B carbapenemase POM-1, further confirming that this carbapenemase is naturally produced in this environmental species. Finally, several isolates co-producing 16S rRNA methylases (ArmA, RmtC) and/or extended-spectrum β-lactamases (CTX-M-9, CTX-M-15) were also identified. Conclusion This study revealed the presence and diversity of clinically-relevant antimicrobial-resistant bacteria in the environment in Nigeria.
- Subjects :
- 0301 basic medicine
Microbiology (medical)
030106 microbiology
Immunology
Nigeria
Chryseobacterium gleum
Environment
Microbiology
beta-Lactamases
Carbapenemase
03 medical and health sciences
0302 clinical medicine
Bacterial Proteins
Pseudomonas
RNA, Ribosomal, 16S
Immunology and Allergy
030212 general & internal medicine
2. Zero hunger
Chryseobacterium
biology
16S ribosomal RNA
biology.organism_classification
Enterobacteriaceae
QR1-502
3. Good health
Acinetobacter baumannii
Stenotrophomonas maltophilia
Burkholderia
Gram-negative bacteria
Pseudomonas otitidis
Bacteria
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Journal of Global Antimicrobial Resistance, Vol 21, Iss, Pp 321-323 (2020)
- Accession number :
- edsair.doi.dedup.....7b4d85d13131aaa1da7f63e4933a1323