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A Lock Free Approach To Parallelize The Cellular Potts Model: Application To Ductal Carcinoma In Situ
- Source :
- Journal of Integrative Bioinformatics, Vol 17, Iss 1, Pp 730-45 (2020), Journal of Integrative Bioinformatics, Journal of Integrative Bioinformatics. 2020; 20190070, RODIN. Repositorio de Objetos de Docencia e Investigación de la Universidad de Cádiz, Agencia Estatal de Meteorología (AEMET), RODIN: Repositorio de Objetos de Docencia e Investigación de la Universidad de Cádiz, Universidad de Cádiz
- Publication Year :
- 2020
- Publisher :
- De Gruyter, 2020.
-
Abstract
- In the field of computational biology, in order to simulate multiscale biological systems, the Cellular Potts Model (CPM) has been used, which determines the actions that simulated cells can perform by determining a hamiltonian of energy that takes into account the influence that neighboring cells exert, under a wide range of parameters. There are some proposals in the literature that parallelize the CPM; in all cases, either lock-based techniques or other techniques that require large amounts of information to be disseminated among parallel tasks are used to preserve data coherence. In both cases, computational performance is limited. This work proposes an alternative approach for the parallelization of the model that uses transactional memory to maintain the coherence of the information. A Java implementation has been applied to the simulation of the ductal adenocarcinoma of breast in situ (DCIS). Times and speedups of the simulated execution of the model on the cluster of our university are analyzed. The results show a good speedup.
- Subjects :
- Speedup
Java
DCIS
Computer science
Breast Neoplasms
Parallel computing
Cellular Automata
03 medical and health sciences
0302 clinical medicine
parallel
Non-blocking algorithm
Humans
Computer Simulation
Cellular Potts Model
030304 developmental biology
computer.programming_language
0303 health sciences
Multi-core processor
cellular automata
speedup
Cellular Potts model
multicore
Transactional memory
Computational Biology
General Medicine
software transactional memory
Cellular automaton
cellular potts model
Carcinoma, Intraductal, Noninfiltrating
dcis
030220 oncology & carcinogenesis
Software transactional memory
computer
TP248.13-248.65
Research Article
Biotechnology
Subjects
Details
- Language :
- English
- ISSN :
- 16134516
- Volume :
- 17
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Journal of Integrative Bioinformatics
- Accession number :
- edsair.doi.dedup.....7b68e654ad72bf79fb8e9dc70827a301