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A Lock Free Approach To Parallelize The Cellular Potts Model: Application To Ductal Carcinoma In Situ

Authors :
Alberto Salguero
Antonio J. Tomeu
Ingeniería Informática
Source :
Journal of Integrative Bioinformatics, Vol 17, Iss 1, Pp 730-45 (2020), Journal of Integrative Bioinformatics, Journal of Integrative Bioinformatics. 2020; 20190070, RODIN. Repositorio de Objetos de Docencia e Investigación de la Universidad de Cádiz, Agencia Estatal de Meteorología (AEMET), RODIN: Repositorio de Objetos de Docencia e Investigación de la Universidad de Cádiz, Universidad de Cádiz
Publication Year :
2020
Publisher :
De Gruyter, 2020.

Abstract

In the field of computational biology, in order to simulate multiscale biological systems, the Cellular Potts Model (CPM) has been used, which determines the actions that simulated cells can perform by determining a hamiltonian of energy that takes into account the influence that neighboring cells exert, under a wide range of parameters. There are some proposals in the literature that parallelize the CPM; in all cases, either lock-based techniques or other techniques that require large amounts of information to be disseminated among parallel tasks are used to preserve data coherence. In both cases, computational performance is limited. This work proposes an alternative approach for the parallelization of the model that uses transactional memory to maintain the coherence of the information. A Java implementation has been applied to the simulation of the ductal adenocarcinoma of breast in situ (DCIS). Times and speedups of the simulated execution of the model on the cluster of our university are analyzed. The results show a good speedup.

Details

Language :
English
ISSN :
16134516
Volume :
17
Issue :
1
Database :
OpenAIRE
Journal :
Journal of Integrative Bioinformatics
Accession number :
edsair.doi.dedup.....7b68e654ad72bf79fb8e9dc70827a301