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Does the high-intensity zone (HIZ) of lumbar Intervertebral discs always represent an annular fissure?
- Source :
- European radiology. 27(3)
- Publication Year :
- 2015
-
Abstract
- The aim of this study was to examine high-intensity zone (HIZ) characteristics on both T1- and T2-weighted sagittal magnetic resonance (MR) images, and to reveal their exact nature. Seventy-three patients with low back pain and HIZs (identified on T2-weighted images) were included. Patients, aged 25-80 years (mean 51), were divided into two groups: the ‘single-HIZ’ group exhibited HIZs only on T2-weighted images, while the ‘dual-HIZ’ group exhibited HIZs on both T2-weighted and T1-weighted images. Tissue corresponding to the HIZ was harvested from surgery for analysis. Eighty-two discs were studied, from 39 patients with single HIZs, 30 with dual HIZs, and four with both in the posterior annulus. HIZ volume, volume ratio, and signal intensity on T2-weighted images from the dual-HIZ group were significantly greater. Surgery was able to successfully restore patients’ ability in both groups, while conservative treatments were less effective for patients with dual HIZs. Histology revealed outer annular fissures invaded by granulation tissue in the single-HIZ group. In dual-HIZ discs, Von Kossa staining and CT scans showed more calcified or ossified lesions (94.1 vs. 0 %, P
- Subjects :
- Adult
Male
Lumbar vertebrae
03 medical and health sciences
0302 clinical medicine
Lumbar
medicine
Humans
Radiology, Nuclear Medicine and imaging
Von Kossa stain
Intervertebral Disc
Radiculopathy
Aged
Aged, 80 and over
030222 orthopedics
Lumbar Vertebrae
medicine.diagnostic_test
business.industry
Ultrasound
Granulation tissue
Calcinosis
Magnetic resonance imaging
Intervertebral disc
General Medicine
Anatomy
Middle Aged
Magnetic Resonance Imaging
Sagittal plane
medicine.anatomical_structure
Female
business
Low Back Pain
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 14321084
- Volume :
- 27
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- European radiology
- Accession number :
- edsair.doi.dedup.....7b8f6be527531b58386ba7d0a8b1f2e1