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Diffusion Tensor Imaging of White Matter Injury Caused by Prematurity-Induced Hypoxic-Ischemic Brain Damage
- Source :
- Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
- Publication Year :
- 2016
- Publisher :
- International Scientific Information, Inc., 2016.
-
Abstract
- BACKGROUND This investigation aimed to evaluate changes in apparent diffusion coefficient (ADC) and fractional anisotropy (FA) of white matter injury (WMI) in preterm neonates with hypoxic-ischemic encephalopathy (HIE) using diffusion tension imaging (DTI). MATERIAL AND METHODS Thirty-eight neonates less than 37 weeks of gestation with leukoencephalopathy (as observation group) and 38 full-term infants with no leukoencephalopathy (as control group) were selected from the Neonatal Care Center in Taian Central Hospital from January 2012 to December 2013. A DTI scan was obtained within 1 week after birth. RESULTS In the observation group, on both sides the ADC values in regions of interest (ROI) of white matter, lesions were greater and FA values were lower than in the control group. ADC and FA values in genu and splenum of corpus callosum were statistically different between the mild and severe injury groups (p
- Subjects :
- Male
Brain damage
Corpus callosum
030218 nuclear medicine & medical imaging
White matter
Leukoencephalopathy
03 medical and health sciences
0302 clinical medicine
Leukoencephalopathies
Clinical Research
Fractional anisotropy
medicine
Humans
Effective diffusion coefficient
Retrospective Studies
medicine.diagnostic_test
business.industry
Infant, Newborn
Magnetic resonance imaging
General Medicine
medicine.disease
White Matter
Magnetic Resonance Imaging
Diffusion Magnetic Resonance Imaging
Diffusion Tensor Imaging
medicine.anatomical_structure
Brain Injuries
Case-Control Studies
Hypoxia-Ischemia, Brain
Anisotropy
Female
medicine.symptom
Nuclear medicine
business
Infant, Premature
030217 neurology & neurosurgery
Diffusion MRI
Subjects
Details
- ISSN :
- 16433750
- Volume :
- 22
- Database :
- OpenAIRE
- Journal :
- Medical Science Monitor
- Accession number :
- edsair.doi.dedup.....7bb0c9e454b886ec6e0fb0df3ebb8205