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Health-related quality of life is maintained in hemodialysis patients receiving pharmaceutical care: A 2-year randomized, controlled study
- Source :
- Hemodialysis International. 13:72-79
- Publication Year :
- 2009
- Publisher :
- Wiley, 2009.
-
Abstract
- End-stage renal disease and initiation of hemodialysis (HD) adversely affect health-related quality of life (HRQOL). There are currently no data evaluating the effect of pharmaceutical care (PC) on HRQOL in HD patients. HD patients were randomized to receive PC; one-on-one, in-depth medication reviews conducted by a clinical pharmacist or Standard of Care (SOC); and brief medication reviews conducted by dialysis nurses. The renal quality of life profile (RQLP) was administered at baseline and then at 1 and 2 years after study initiation. The RQLP is a 43-item questionnaire that has 5 dimensions: Eating/Drinking, Physical Activities, Leisure Time, Psychosocial Activities, and Impact of Treatment, where increasing scores reflect worsening of HRQOL. A total of 107 patients were enrolled (SOC: n=46; PC: n=61). Besides gender, there were no differences in the demographics or the baseline total RQLP scores. The mean+/-SD total RQLP scores at Year 1 were significantly worse in SOC compared with PC (88+/-31 vs. 71+/-34, respectively; P=0.03). Significant worsening of Eating and Drinking (5.9+/-3.3 vs. 4.4+/-3.1, respectively; P=0.04), Physical Activities (37+/-13.6 vs. 30+/-16.3, respectively; P=0.04), and Leisure Time scores (8.3+/-3.4 vs. 5.9+/-3.6, respectively; P=0.03) was also observed in the SOC group. After 2 years, only the SOC patients had worsening of Leisure Time (7.5+/-3.0 vs. 5.2+/-3.9, respectively; P=0.04). No other parameters were different between the groups after 2 years. These data indicate that patients who have clinical care provided by pharmacists do not have worsened HRQOL after 1 year and are able to maintain HRQOL for an additional year.
- Subjects :
- Adult
Male
Pediatrics
medicine.medical_specialty
Health Status
medicine.medical_treatment
Pharmacists
law.invention
Randomized controlled trial
Quality of life
Renal Dialysis
law
medicine
Humans
Dialysis
Aged
Sex Characteristics
business.industry
Hematology
Middle Aged
Clinical pharmacy
Pharmaceutical care
Nephrology
Pharmaceutical Services
Quality of Life
Female
Hemodialysis
business
Psychosocial
Sex characteristics
Subjects
Details
- ISSN :
- 15424758 and 14927535
- Volume :
- 13
- Database :
- OpenAIRE
- Journal :
- Hemodialysis International
- Accession number :
- edsair.doi.dedup.....7bdcee12e1c02e512e28ec5e804e9f15
- Full Text :
- https://doi.org/10.1111/j.1542-4758.2009.00328.x