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Supplementary Figures from Ribosomal Protein Rpl22 Controls the Dissemination of T-cell Lymphoma

Authors :
David L. Wiest
Joseph R. Testa
Shawn P. Fahl
Sang-Yun Lee
Nehal Solanki-Patel
Noa Greenberg-Kushnir
Jason E. Stadanlick
Kathy Q. Cai
Shuyun Rao
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

This file contains supplementary figures 1-4. Supplementary Figure 1 provides supporting information for the effects of Rpl22 loss on thymic cellularity and supports Figure 1. Supplementary Figure 2 describes the phenotypes of periperhal T lineage cells, both normal and transformed, in Rpl22-sufficient and Rpl22-deficient mice. It supports the data in Figure 3. Supplementary Figure 3 depicts the maturation of single positive thymocytes in MyrAkt Tg Rpl22-deficient mice, revealing that maturation is not impaired. These data support Figure 5. Supplementary figure 4 depicts the effect of Rpl22 mutation on expression of KLF2 and S1PR1 in human T-ALL. It supports the data in Figure 6.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....7be51f3c5706a37ce093a350655aac74
Full Text :
https://doi.org/10.1158/0008-5472.22408754.v1