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Rapid Estimation of T1 for Quantitative NMR

Authors :
Ran Wei
Dušan Uhrín
Claire L Dickson
Guy C. Lloyd-Jones
Source :
Wei, R, Dickson, C L, Uhrin, D & Lloyd-jones, G C 2021, ' Rapid Estimation of T 1 for Quantitative NMR ', Journal of Organic Chemistry, vol. 86, no. 13, pp. 9023–9029 . https://doi.org/10.1021/acs.joc.1c01007
Publication Year :
2021
Publisher :
American Chemical Society (ACS), 2021.

Abstract

Quantitative NMR spectroscopy (qNMR) is an essential tool in organic chemistry, with applications including reaction monitoring, mechanistic analysis, and purity determination. Establishing the correct acquisition rate for consecutive qNMR scans requires knowledge of the longitudinal relaxation time constants (T1) for all of the nuclei being monitored. We report a simple method that is about 10-fold faster than the conventional inversion recovery technique for the estimation of T1.

Details

ISSN :
15206904 and 00223263
Volume :
86
Database :
OpenAIRE
Journal :
The Journal of Organic Chemistry
Accession number :
edsair.doi.dedup.....7bee9f5a9da819638a5d31590b2b4b31
Full Text :
https://doi.org/10.1021/acs.joc.1c01007