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Complement activation in patients with COVID-19: A novel therapeutic target
- Source :
- Journal of Allergy and Clinical Immunology, The Journal of Allergy and Clinical Immunology
- Publication Year :
- 2020
- Publisher :
- Elsevier BV, 2020.
-
Abstract
- The pathophysiology of the severe complications of COVID-19 is still unclear. We report preliminary data providing evidence of complement activation in patients with COVID-19 with different degrees of respiratory failure.
- Subjects :
- Adult
Male
2019-20 coronavirus outbreak
C5a
Coronavirus disease 2019 (COVID-19)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Pneumonia, Viral
Immunology
Complement
Complement C5a
Complement Membrane Attack Complex
Article
Betacoronavirus
Humans
Immunology and Allergy
Medicine
In patient
Complement Activation
Pandemics
Aged
Aged, 80 and over
SARS-CoV-2
business.industry
COVID-19
Middle Aged
sC5b-9
Complement system
Cancer research
Female
Coronavirus Infections
business
Complement membrane attack complex
Subjects
Details
- ISSN :
- 00916749
- Volume :
- 146
- Database :
- OpenAIRE
- Journal :
- Journal of Allergy and Clinical Immunology
- Accession number :
- edsair.doi.dedup.....7c0d6559ab9aa29ce01d89da510bb6bd
- Full Text :
- https://doi.org/10.1016/j.jaci.2020.05.006