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Temporal patterns of premature atrial complexes predict atrial fibrillation occurrence in bradycardia patients continuously monitored through pacemaker diagnostics
- Publication Year :
- 2020
-
Abstract
- The frequency of premature atrial complexes (PACs) has been related with atrial fibrillation (AF) occurrence and adverse prognosis. Research objective was to evaluate whether temporal patterns of PACs are directly associated with AF onset in pacemaker patients with continuous monitoring of the atrial rhythm. Overall, 193 pacemaker patients (49% female, 72 ± 9 years old), enrolled in a national registry, were analyzed. Frequency of daily PACs was measured in a 14-day initial observation period, during which patients were in sinus rhythm. In the following period, temporal occurrence and frequency of daily PACs and eventual onset of AF were derived by pacemaker diagnostics. In the run-in period, median PACs frequency was 614 PACs/day (interquartile range 70–3056). Subsequently, in a median follow-up of 6 months, AF occurred in 109 patients, in particular in 37/96 (38.5%) patients with a PAC rate
- Subjects :
- Bradycardia
Male
medicine.medical_specialty
Pacemaker, Artificial
endocrine system diseases
education
030204 cardiovascular system & hematology
Risk Assessment
03 medical and health sciences
0302 clinical medicine
Interquartile range
Predictive Value of Tests
health services administration
Internal medicine
Atrial Fibrillation
Internal Medicine
medicine
Humans
Sinus rhythm
030212 general & internal medicine
Registries
Aged
Retrospective Studies
Proportional hazards model
business.industry
Hazard ratio
food and beverages
Atrial fibrillation
medicine.disease
Prognosis
humanities
Confidence interval
PREMATURE ATRIAL COMPLEXES
Heart Disease Risk Factors
Emergency Medicine
Cardiology
Electrocardiography, Ambulatory
Monitoring
Pacemaker
Premature atrial complexes
Female
Atrial Premature Complexes
medicine.symptom
business
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....7c24314966899ccea7f7380428de0c38