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Sclerosing Cholangitis Like Changes on Magnetic Resonance Cholangiography in Patients with Drug Induced Liver Injury
- Publication Year :
- 2018
-
Abstract
- Drug-induced liver injury can lead to changes of the biliary tree that resemble sclerosing cholangitis. These changes can be seen on magnetic resonance cholangiopancreatography. Idiosyncratic drug-induced liver injury (DILI) has a variable presentation including cholestatic liver injury,1 in which case magnetic resonance imaging (MRI) is often performed to exclude pancreaticobiliary causes of obstruction. Sclerosing cholangitis (SC)-like changes on imaging have been described anecdotally with DILI.2,3 A recent study of 25 consecutive, unselected DILI patients found that 10% had SC-like changes on magnetic resonance cholangiopancreatography (MRCP).4 The aim of the current study was to identify the clinical features of patients enrolled in the U.S. Drug Induced Liver Injury Network (DILIN) prospective study who had SC-like changes on MRCP.
- Subjects :
- Drug
Male
medicine.medical_specialty
media_common.quotation_subject
Cholangitis, Sclerosing
Variable presentation
Gastroenterology
Article
03 medical and health sciences
0302 clinical medicine
Cholangiography
Internal medicine
medicine
Humans
In patient
Prospective Studies
Prospective cohort study
skin and connective tissue diseases
media_common
Liver injury
Magnetic resonance cholangiopancreatography
Hepatology
medicine.diagnostic_test
business.industry
fungi
food and beverages
Magnetic resonance imaging
Middle Aged
medicine.disease
Magnetic Resonance Imaging
United States
030220 oncology & carcinogenesis
030211 gastroenterology & hepatology
Female
sense organs
Chemical and Drug Induced Liver Injury
business
human activities
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....7c8003a48072ce404db94b5078b7eaba