Back to Search
Start Over
The interpretation of liver function tests in pregnancy
- Source :
- Best practiceresearch. Clinical gastroenterology.
- Publication Year :
- 2019
-
Abstract
- Abnormal liver tests occur in 3-5% of pregnancies and show many different causes. Although alterations of liver enzymes could be a physiological phenomenon, it may also reflect potential severe liver injury, necessitating further assessment and accurate management. The work-up has to consider liver diseases specific of pregnancy and non pregnancy-related liver damage (coincidental and pre-existing to pregnancy). Pre-existing liver diseases during pregnancy are relatively uncommon, as pregnant women are generally young and healthy. Liver diseases unique to pregnancy are intrahepatic cholestasis of pregnancy, the HELLP syndrome (haemolysis, elevated liver enzymes, low platelets) and acute fatty liver of pregnancy. These disorders may result in foetal distress, severe liver damage and sometime hepatic failure; for these reasons the diagnostic work-up and treatment must be very fast. This review focuses on the management of pregnant women with altered liver function tests. Furthermore, the main liver diseases specific of pregnancy are described.
- Subjects :
- HELLP syndrome
Physiology
Transaminase
Acute fatty liver of pregnancy
Cholestasis
Liver Function Tests
Pregnancy
medicine
Humans
Liver injury
medicine.diagnostic_test
business.industry
Liver Function Test
Liver Disease
Liver Diseases
Gastroenterology
medicine.disease
Haemolysis
Pregnancy Complications
Cholestasi
Female
Liver function tests
business
Cholestasis of pregnancy
Human
Subjects
Details
- ISSN :
- 15321916
- Database :
- OpenAIRE
- Journal :
- Best practiceresearch. Clinical gastroenterology
- Accession number :
- edsair.doi.dedup.....7cb2c3d6a083304333c801d5466f4485