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Significant reduction in depressive symptoms among patients with moderately-severe to severe depressive symptoms after participation in a therapist-supported, evidence-based mobile health program delivered via a smartphone app
- Source :
- Internet Interventions, Internet Interventions, Vol 25, Iss, Pp 100408-(2021)
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Depression is a debilitating disorder associated with poor health outcomes, including increased comorbidity and early mortality. Despite the advent of new digital health interventions, few have been tested among patients with more severe forms of depression. As such, in an intent-to-treat study we examined whether 218 patients with at least moderately severe depressive symptoms (PHQ-9 ≥ 15) experienced significant reductions in depressive symptoms after participation in a therapist-supported, evidence-based mobile health (mHealth) program, Meru Health Program (MHP). Patients with moderately severe and severe depressive symptoms at pre-program assessment experienced significant decreases in depressive symptoms at end-of treatment (mean [standard deviation] PHQ-9 reduction = 8.30 [5.03], Hedges' g = 1.64, 95% CI [1.44, 1.85]). Also, 34% of patients with at least moderately severe depressive symptoms at baseline and 29.9% of patients with severe depressive symptoms (PHQ-9 ≥ 20) at baseline responded to the intervention at end-of-treatment, defined as experiencing ≥50% reduction in PHQ-9 score and a post-program PHQ-9 score lower than 10. Limitations include use lack of a control group and no clinical diagnostic information. Future randomized trials are warranted to test the MHP as a scalable solution for patients with more severe depressive symptoms.<br />Highlights • 218 patients with severe depression participated in a mHealth intervention. • Patients had significant decreases in depression (Hedges' g = 1.64). • Improvements were maintained at 3- and 6-months post-program. • Nearly one-third of patients responded to the intervention at end-of-treatment. • Future randomized trials are needed to test the intervention as a scalable solution.
- Subjects :
- 050103 clinical psychology
medicine.medical_specialty
MHP, Meru Health Program
Evidence-based practice
Digital health interventions
Psychological intervention
Health Informatics
Information technology
law.invention
03 medical and health sciences
0302 clinical medicine
Randomized controlled trial
law
Internal medicine
Intervention (counseling)
medicine
Psychology
HRVB, heart rate variability biofeedback
0501 psychology and cognitive sciences
030212 general & internal medicine
Severe depression
mHealth
Depression (differential diagnoses)
Depression
business.industry
TMS, transcranial magnetic stimulation
ITT, intention-to-treat
05 social sciences
T58.5-58.64
medicine.disease
Digital health
Comorbidity
Full length Article
PHQ-9, Patient Health Questionnaire-9 item survey
BF1-990
ECT, electroconvulsive therapy
Mobile health interventions
business
Subjects
Details
- ISSN :
- 22147829
- Volume :
- 25
- Database :
- OpenAIRE
- Journal :
- Internet Interventions
- Accession number :
- edsair.doi.dedup.....7cf8c2c50fccf6e523772521fe634433