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In vitro antiprotozoal and cytotoxic activity of ethnopharmacologically selected guinean plants
- Source :
- Planta medica: natural products and medicinal plant research
- Publication Year :
- 2014
-
Abstract
- Based on an ethnobotanical survey, 41 Guinean plant species widely used in the traditional treatment of fever and/or malaria were collected. From these, 74 polar and apolar extracts were prepared and tested for their in vitro antiprotozoal activity along with their cytotoxicity on MRC-5 cells. A potent activity (IC50 100. These results may validate at least in part the traditional use of some of the plant species.
- Subjects :
- medicine.drug_class
Trypanosoma brucei brucei
Antiprotozoal Agents
Drug Evaluation, Preclinical
Ethnobotany
Pharmaceutical Science
Trypanosoma brucei
Analytical Chemistry
parasitic diseases
Drug Discovery
Botany
medicine
Leishmania infantum
Biology
Spondias mombin
Pavetta
Pharmacology
Combretum glutinosum
Plants, Medicinal
biology
Traditional medicine
Plant Extracts
Pharmacology. Therapy
Organic Chemistry
Terminalia macroptera
biology.organism_classification
Guiera senegalensis
Complementary and alternative medicine
Antiprotozoal
Molecular Medicine
Guinea
Subjects
Details
- ISSN :
- 14390221 and 00320943
- Volume :
- 80
- Issue :
- 15
- Database :
- OpenAIRE
- Journal :
- Planta medica
- Accession number :
- edsair.doi.dedup.....7d11f9603a3024f44a094c2493b50da4