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In vitro antiprotozoal and cytotoxic activity of ethnopharmacologically selected guinean plants

Authors :
A. Keïta
Paul Cos
Abdoulaye Diallo
M. S. T. Diallo
Aliou Mamadou Balde
Aïssata Camara
S. Diané
E.S. Baldé
M. Traoré
Louis Maes
Mamadou Aliou Baldé
Luc Pieters
Source :
Planta medica: natural products and medicinal plant research
Publication Year :
2014

Abstract

Based on an ethnobotanical survey, 41 Guinean plant species widely used in the traditional treatment of fever and/or malaria were collected. From these, 74 polar and apolar extracts were prepared and tested for their in vitro antiprotozoal activity along with their cytotoxicity on MRC-5 cells. A potent activity (IC50 100. These results may validate at least in part the traditional use of some of the plant species.

Details

ISSN :
14390221 and 00320943
Volume :
80
Issue :
15
Database :
OpenAIRE
Journal :
Planta medica
Accession number :
edsair.doi.dedup.....7d11f9603a3024f44a094c2493b50da4