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Drug-Eluting Stents for Treatment of Peripheral Artery Disease
- Source :
- American Journal of Cardiovascular Drugs. 18:175-180
- Publication Year :
- 2018
- Publisher :
- Springer Science and Business Media LLC, 2018.
-
Abstract
- Endovascular intervention is a mainstay treatment of peripheral artery disease (PAD) in addition to aggressive risk factor modification and exercise programs in patients with favorable anatomy or in those who are considered too high risk for surgical intervention. Treatment with percutaneous transluminal angioplasty (PTA) and bare metal stents (BMS) has been limited by high rates of in-stent restenosis (ISR) requiring repeat revascularization. Drug-eluting stents (DES), developed and designed to reduce ISR, offer a promising solution to the current challenges in endovascular management of PAD. Several randomized clinical trials have shown improved short- and mid-term outcomes with DES as compared with both PTA and BMS. Herein we provide an up-to-date review of the current literature on DES use in PAD.
- Subjects :
- Drug
medicine.medical_specialty
Percutaneous
Arterial disease
media_common.quotation_subject
Disease
030204 cardiovascular system & hematology
law.invention
Peripheral Arterial Disease
03 medical and health sciences
Postoperative Complications
0302 clinical medicine
Pharmacotherapy
Randomized controlled trial
Restenosis
law
medicine
Humans
Pharmacology (medical)
030212 general & internal medicine
Risk factor
Randomized Controlled Trials as Topic
media_common
business.industry
Endovascular Procedures
Drug-Eluting Stents
General Medicine
medicine.disease
Surgery
body regions
Treatment Outcome
surgical procedures, operative
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 1179187X and 11753277
- Volume :
- 18
- Database :
- OpenAIRE
- Journal :
- American Journal of Cardiovascular Drugs
- Accession number :
- edsair.doi.dedup.....7df506ce49ceb678feb9df6b21620d1a