Increased expression of ORMDL3 in allergic asthma: a case control and in vitro study

Authors :: Joanna Nowakowska
Anna Olechnowicz
Wojciech Langwiński
Oliwia Koteluk
Żaneta Lemańska
Kacper Jóźwiak
Kacper Kamiński
Wojciech Łosiewski
John Stegmayr
Darcy Wagner
Hani N. Alsafadi
Sandra Lindstedt
Maria Dziuba
Antonina Bielicka
Zuzanna Graczyk
Aleksandra Szczepankiewicz
Source :: Journal of Asthma. 60:458-467
Publication Year :: 2022
Publisher :: Informa UK Limited, 2022.
Abstract: Asthma is the most frequent chronic disease in children. One of the most replicated genetic findings in childhood asthma is theThe purpose of this study was to analyzeIn the study we included 416 subject, 223 asthmatic children and 193 healthy control subjects. The analysis of two SNPs (rs3744246 and rs8076131) was performed using genotyping with TaqMan probes. The methylation of theWe found thatIncreased

Subjects :: Pulmonary and Respiratory Medicine
Pediatrics, Perinatology and Child Health
Immunology and Allergy

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