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Soulieoside O, a new cyclolanostane triterpenoid glycoside from Souliea vaginata
- Source :
- Journal of Asian natural products research. 19(12)
- Publication Year :
- 2017
-
Abstract
- A new cyclolanostane triterpenoid glycoside, soulieoside O (1), together with 25-O-acetylcimigenol-3-O-β-d-xylopyranoside (2) and cimigenol-3-O-β-d-xylopyranoside (3), was isolated from the rhizomes of Souliea vaginata. Their structures were characterized by spectroscopic analysis and chemical methods. The new compound showed moderate inhibitory activity against three human cancer cell lines with IC50 values of 9.3–22.5 μM.
- Subjects :
- Stereochemistry
Pharmaceutical Science
01 natural sciences
Analytical Chemistry
Inhibitory Concentration 50
Triterpenoid
Drug Discovery
Ic50 values
Souliea vaginata
Humans
Glycosides
Cytotoxicity
Nuclear Magnetic Resonance, Biomolecular
Pharmacology
chemistry.chemical_classification
Molecular Structure
010405 organic chemistry
Chemistry
Organic Chemistry
Glycoside
Stereoisomerism
General Medicine
Antineoplastic Agents, Phytogenic
Triterpenes
0104 chemical sciences
Rhizome
010404 medicinal & biomolecular chemistry
Complementary and alternative medicine
Cell culture
Molecular Medicine
Drug Screening Assays, Antitumor
Ranunculaceae
Human cancer
Drugs, Chinese Herbal
Subjects
Details
- ISSN :
- 14772213
- Volume :
- 19
- Issue :
- 12
- Database :
- OpenAIRE
- Journal :
- Journal of Asian natural products research
- Accession number :
- edsair.doi.dedup.....7e1e0087ff9b2b66622ae24e9a83ca9f