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Supplementary Figures 1-5 from Genome-wide DNA Methylation Events in TMPRSS2–ERG Fusion-Negative Prostate Cancers Implicate an EZH2-Dependent Mechanism with miR-26a Hypermethylation

Authors :
Michal R. Schweiger
Hans Lehrach
Holger Sültmann
Thorsten Schlomm
Guido Sauter
Mark A. Rubin
Francesca Demichelis
Ronald Simon
Markus Graefen
Christoph Plass
Rainer Claus
Bernd Timmermann
Andrea Wunderlich
Christina Röhr
Melanie Isau
Behnam Sayanjali
Christina Grimm
Andreas Dahl
Ruprecht Kuner
Jan C. Brase
Mark Laible
Maria Fälth
Martin Kerick
Axel Fischer
Stefan T. Börno
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

PDF file - 947K, Supplementary Fig. S1. Differential methylations in PCa validated by BS-MS experiments. Supplementary Fig. S2. DNA-Methylomes of prostate cancer differ significantly from normal tissues. Supplementary Fig. S3. Global differences in DNA methylation patterns between tumor, normal, FUS+ and FUS- samples. Supplementary Fig. S4 Patientwise patterns of promoter hypermethylation and corresponding gene expression of EZH2 target genes. Supplementary Fig. S5 Methylation of the miRNA-26a genomic region

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....7eea8631ec06151a01784680eb84a063
Full Text :
https://doi.org/10.1158/2159-8290.22528505.v1