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Assessment of left ventricular deformation in patients with Ebstein’s anomaly by cardiac magnetic resonance tissue tracking
- Source :
- European Journal of Radiology. 89:20-26
- Publication Year :
- 2017
- Publisher :
- Elsevier BV, 2017.
-
Abstract
- The aim of this study was to clarify the feasibility of myocardial strain using cardiovascular magnetic resonance (CMR) for the evaluation of left ventricular (LV) deformation in patients with Ebstein's anomaly (EA).We recruited 32 patients with EA and 30 controls for CMR examination and measured LV function, dimension and tissue tracking parameters (the global and regional radial, circumferential and longitudinal peak strain), together with the right ventricle (RV) dimension. LV strain parameters were compared among the controls, patients with preserved LV ejection fraction (LVEF; ≥55%), and patients with reduced LVEF (55%). Pearson's correlation was used to evaluate relationships between tissue tracking parameters with the RVEDD/LVEDD index and LVEF. An ROC analysis was also performed to determine whether the cut-off values for PS could be used to differentiate LV dysfunction between patients with EA and controls. The intraclass correlation coefficient (ICC) was used to assess the inter- and intra-observer variability.The global strain parameters all decreased significantly in the EA group compared with the control group (all P0.05). Furthermore, the global radial and circumferential peak strain (PS) were obviously even lower in the reduced LVEF group than the strain measured in preserved LVEF groups (28.64% vs. 37.39%, p0.05; and -8.20% vs. -17.89%; p0.05; respectively). The regional strain abnormalities in EA patients were mainly involved in basal and middle segments. The results also demonstrated a significant correlation between the ratio of the RV end-diastolic dimension to the LV end-diastolic dimension (RVEDD/LVEDD index) with the global circumferential PS (r=0.508) and the longitudinal PS (r=0.474), as well as a good correlation between radial PS and LVEF (r=0.465). The ICCs for intra- and inter-observer variability were 0.797-0.904 and 0.701-0.896.LV strain serves an earlier and more comprehensive measurement of LV dysfunction than LVEF in EA, which could potentially be included as a supplementary diagnostic procedure in the evaluation of EA.
- Subjects :
- Adult
Male
medicine.medical_specialty
Tissue tracking
Heart Ventricles
030204 cardiovascular system & hematology
Ventricular Function, Left
Ventricular Dysfunction, Left
03 medical and health sciences
0302 clinical medicine
Ebstein's anomaly
Internal medicine
medicine
Humans
Radiology, Nuclear Medicine and imaging
In patient
cardiovascular diseases
030212 general & internal medicine
Observer Variation
Ejection fraction
medicine.diagnostic_test
business.industry
Magnetic resonance imaging
General Medicine
medicine.disease
Magnetic Resonance Imaging
Global strain
Ebstein Anomaly
medicine.anatomical_structure
ROC Curve
Ventricle
cardiovascular system
Cardiology
Female
business
Cardiac magnetic resonance
Subjects
Details
- ISSN :
- 0720048X
- Volume :
- 89
- Database :
- OpenAIRE
- Journal :
- European Journal of Radiology
- Accession number :
- edsair.doi.dedup.....7f0ca8cc85c919ac6c3e2af48ad2ff0b