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Effects of ischemic postconditioning on expressions of pentraxin-related protein 3 and neutrophil CD11b in the plasma of patients with acute myocardial infarction after percutaneous coronary intervention
- Source :
- Pakistan Journal of Medical Sciences
- Publication Year :
- 1969
- Publisher :
- Pakistan Journal of Medical Sciences, 1969.
-
Abstract
- Objective: To evaluate the effects of ischemic postconditioning on expressions of pentraxin-related protein 3 (PTX3) and neutrophil CD11b in the plasma of patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI). Methods: Fifty-six patients who had AMI with ST-segment elevation were randomly divided into a control group and an ischemic postconditioning group (n=28). Both groups received emergency PCI. After recanalization of infarct-related arteries, the control group did not receive intervention within three minutes, while the ischemic postconditioning group was treated by low-pressure filling and emptying of balloon within one minute. The plasma expressions of PTX3 before and 24 hour after PCI were detected by ELISA, and those of neutrophil CD11b were detected by flow cytometry. Results: PTX3 and neutrophil CD11b expressions of the two groups were similar before PCI, but those of the ischemic postconditioning group significantly decreased 24 hour after PCI (P
- Subjects :
- medicine.medical_specialty
medicine.medical_treatment
Inflammatory response
Balloon
Cell adhesion molecule
Internal medicine
medicine
cardiovascular diseases
Myocardial infarction
Ischemic postconditioning
biology
business.industry
Pentraxin-related protein 3
Neutrophil
Percutaneous coronary intervention
General Medicine
PTX3
medicine.disease
Integrin alpha M
Conventional PCI
Cardiology
biology.protein
Original Article
business
Subjects
Details
- ISSN :
- 1681715X
- Volume :
- 32
- Database :
- OpenAIRE
- Journal :
- Pakistan Journal of Medical Sciences
- Accession number :
- edsair.doi.dedup.....7fb8deca49f6ee9ee6f889eed9d04e65