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Ion channels
- Source :
- Current Biology. 9:R173-R175
- Publication Year :
- 1999
- Publisher :
- Elsevier BV, 1999.
-
Abstract
- A combination of crystallographic and mutagenesis studies on the HERG K + channel, a key determinant of cardiac excitability, has suggested how the protein's extramembraneous amino-terminal domain might act as a ‘molecular brake' that slows down channel deactivation.
Details
- ISSN :
- 09609822
- Volume :
- 9
- Database :
- OpenAIRE
- Journal :
- Current Biology
- Accession number :
- edsair.doi.dedup.....7fc798d22b30e228794485a841bdfe50
- Full Text :
- https://doi.org/10.1016/s0960-9822(99)80106-7