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The interaction of an amorphous metal-organic cage-based solid (aMOC) with miRNA/DNA and its application on a quartz crystal microbalance (QCM) sensor

Authors :
Jia-Ying Li
Sheng-Run Zheng
Dian-Mei Li
Ding Ma
Yu-Ping Zhang
Chu-Hong Wu
Wei-Guang Zhang
Xia Jin
Source :
Chemical communications (Cambridge, England). 56(4)
Publication Year :
2019

Abstract

The interaction between an aMOC and miRNA/DNA is studied and the use of a signal probe DNA (spDNA)@aMOC complex as an effective amplifier in a QCM sensor to detect miRNA is developed. The signal can be significantly enhanced, which leads to improved performance when detecting and distinguishing miRNAs.

Details

ISSN :
1364548X
Volume :
56
Issue :
4
Database :
OpenAIRE
Journal :
Chemical communications (Cambridge, England)
Accession number :
edsair.doi.dedup.....7fcd2862fba97f5b7b81c7ad8d4e43af