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FrAnTK: a Frequency-based Analysis ToolKit for efficient exploration of allele sharing patterns in present-day and ancient genomic datasets
- Source :
- G3: Genes|Genomes|Genetics, Moreno-Mayar, J V 2022, ' FrAnTK : a Frequency-based Analysis ToolKit for efficient exploration of allele sharing patterns in present-day and ancient genomic datasets ', G3: Genes, Genomes, Genetics, vol. 12, no. 1, jkab357 . https://doi.org/10.1093/g3journal/jkab357, G3: Genes, Genomes, Genetics, Vol 12, Iss 1 (2021)
- Publication Year :
- 2021
-
Abstract
- Present-day and ancient population genomic studies from different study organisms have rapidly become accessible to diverse research groups worldwide. Unfortunately, as datasets and analyses become more complex, researchers with less computational experience often miss their chance to analyze their own data. We introduce FrAnTK, a user-friendly toolkit for computation and visualization of allele frequency-based statistics in ancient and present-day genome variation datasets. We provide fast, memory-efficient tools that allow the user to go from sequencing data to complex exploratory analyses and visual representations with minimal data manipulation. Its simple usage and low computational requirements make FrAnTK ideal for users that are less familiar with computer programming carrying out large-scale population studies.
- Subjects :
- AcademicSubjects/SCI01140
population genomics
AcademicSubjects/SCI00010
Population
Computer programming
QH426-470
ANCESTRY
Biology
Software and Data Resources
AcademicSubjects/SCI01180
SEQUENCE
Population genomics
user-friendly pipeline
Genetics
education
Molecular Biology
Allele frequency
ancient DNA
Genetics (clinical)
Alleles
computer.programming_language
education.field_of_study
business.industry
Data manipulation language
Computational Biology
Genomics
Python (programming language)
allele sharing statistics
Data science
Visualization
python
POPULATIONS
AcademicSubjects/SCI00960
Perl
business
computer
Software
perl
Subjects
Details
- ISSN :
- 21601836
- Volume :
- 12
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- G3 (Bethesda, Md.)
- Accession number :
- edsair.doi.dedup.....7fce18041d4d73ca4edba408fba3d888
- Full Text :
- https://doi.org/10.1093/g3journal/jkab357