Back to Search
Start Over
Hepatitis B testing, care linkage, and vaccination coverage within a registry of hepatitis C infected patients
- Source :
- Vaccine. 37(16)
- Publication Year :
- 2018
-
Abstract
- Background Hepatitis B virus (HBV) infection testing among persons with hepatitis C virus (HCV) infection is necessary to appropriately care for these patients, yet uptake of HBV testing and vaccination in this population is suboptimal. Methods In a retrospective cohort analysis, we describe the prevalence of hepatitis B testing, linkage to hepatitis B care, and hepatitis B vaccination in patients with HCV infection within a large urban safety-net health system. Using a registry of HCV-infected patients with patient-level electronic health record data, that included demographic, clinical, and laboratory information from 2004 to 2016 from Grady Health System in Atlanta, GA, we describe (1) The prevalence of hepatitis B testing (hepatitis B surface antigen [HBsAg], core antibody [anti-HBc], surface antibody [anti-HBs]); (2) The proportion of HBsAg-positive persons receiving HBV DNA and e-antigen (HBeAg) as indicators for linkage to hepatitis B-directed care; and (3) The proportion of persons receiving hepatitis B vaccine. Results Of 4224 HCV-infected patients, 3629 (86%) had test results for HBsAg and 43 (1.2%) were HBsAg-positive. Of 2342 (55%) with test results for all three HBV serological markers, median age was 60 years, 67% were male, and 83% were African-American, 789 (34%) anti-HBc positive only, 678 (29%) anti-HBc/anti-HBs positive, 190 (8.1%) anti-HBs positive only, and 642 (27%) were HBV-susceptible. Of HBsAg-positive patients, 21% received HBV DNA and 40% HBeAg testing. The proportion of HBV-susceptible patients receiving at least 1 dose of hepatitis B vaccine was 322/642 (50%). Conclusions In a large cohort of HCV-infected patients, we found a high prevalence of current or past HBV infection, but there were gaps in complete hepatitis B testing, hepatitis B-directed care, and hepatitis B vaccination. Strategies are needed to increase hepatitis B testing, linkage to care, and administration of the hepatitis B vaccine for HCV-infected persons in this healthcare system.
- Subjects :
- Adult
Male
HBsAg
medicine.medical_specialty
Hepatitis B virus
Hepatitis B vaccine
Vaccination Coverage
Adolescent
Hepatitis C virus
030231 tropical medicine
Comorbidity
medicine.disease_cause
03 medical and health sciences
Young Adult
0302 clinical medicine
Internal medicine
Prevalence
Medicine
Humans
Hepatitis B Vaccines
Public Health Surveillance
Serologic Tests
030212 general & internal medicine
Registries
Aged
Hepatitis
Aged, 80 and over
General Veterinary
General Immunology and Microbiology
business.industry
Coinfection
Vaccination
Public Health, Environmental and Occupational Health
virus diseases
Hepatitis C
Hepatitis B
Middle Aged
medicine.disease
digestive system diseases
Infectious Diseases
HBeAg
Molecular Medicine
Female
business
Subjects
Details
- ISSN :
- 18732518
- Volume :
- 37
- Issue :
- 16
- Database :
- OpenAIRE
- Journal :
- Vaccine
- Accession number :
- edsair.doi.dedup.....8005fb2d81df27bde370acfe57c3efc4