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Transjugular intrahepatic portosystemic shunts (TIPS) for the prevention of variceal re-bleeding - A two decades experience
- Source :
- PLoS ONE, Vol 13, Iss 1, p e0189414 (2018), PLoS ONE
- Publication Year :
- 2018
- Publisher :
- Public Library of Science (PLoS), 2018.
-
Abstract
- Background and aims Transjugular intrahepatic portosystemic shunts (TIPS) are used in patients with cirrhosis for the prevention of variceal rebleeding. Methods We retrospectively evaluated re-bleeding rate, patency, mortality, and transplant-free survival (TFS) in cirrhotic patients receiving TIPS implantation for variceal bleeding between 1994–2014. Results 286 patients received TIPS (n = 119 bare metal stents, n = 167 polytetrafluorethylene (PTFE)-covered stents) for prevention of variceal re-bleeding. Mean age was 55.1 years, median MELD was 11.8, and the main etiology of cirrhosis was alcoholic liver disease (70%). Median follow-up was 821 days. 67 patients (23%) experienced at least one re-bleeding event. Patients with PTFE-TIPS were at significantly lower risk for variceal re-bleeding than patients with bare metal stents (14% vs. 37%, OR:0.259; p
- Subjects :
- Liver Cirrhosis
Male
Alcoholic liver disease
Cirrhosis
Etiology
medicine.medical_treatment
lcsh:Medicine
Pathology and Laboratory Medicine
Vascular Medicine
0302 clinical medicine
Medicine and Health Sciences
lcsh:Science
Hepatic encephalopathy
Multidisciplinary
medicine.diagnostic_test
Mortality rate
Liver Diseases
Graft Survival
Middle Aged
Oncology
030220 oncology & carcinogenesis
030211 gastroenterology & hepatology
Female
Gastrointestinal Hemorrhage
Research Article
Adult
medicine.medical_specialty
Death Rates
Surgical and Invasive Medical Procedures
Hemorrhage
Gastroenterology and Hepatology
Lower risk
Esophageal and Gastric Varices
Carcinomas
03 medical and health sciences
Signs and Symptoms
Population Metrics
Diagnostic Medicine
Gastrointestinal Tumors
medicine
Humans
Aged
Retrospective Studies
Transplantation
Population Biology
business.industry
lcsh:R
Stent
Biology and Life Sciences
Cancers and Neoplasms
Retrospective cohort study
Endoscopy
Hepatocellular Carcinoma
medicine.disease
Survival Analysis
Surgery
Stent Implantation
lcsh:Q
Portasystemic Shunt, Transjugular Intrahepatic
business
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 13
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.doi.dedup.....8032bfd61f7a591be4675bda3c4cb305