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A New System for Quantitatively Exposing Laboratory Animals by Direct Inhalation
- Source :
- Archives of Environmental Health: An International Journal. 27:376-382
- Publication Year :
- 1973
- Publisher :
- Informa UK Limited, 1973.
-
Abstract
- A system for quantitatively introducing cigarette smoke into the respiratory tract of spontaneously breathing laboratory animals has been developed. At the present time, its use is restricted to animals either with tracheotomies or capable of mouth breathing. The volume, frequency, and duration of cigarette puffing is programmed and not determined by the animal’s respiratory activity. Smoke is loaded into a holding tube and inhaled during normal inhalation. To prevent anoxia, animals are allowed fresh air between puffs. The system can be automated for simultaneously exposing four to eight animals. Except for modest loss of particulate material, the composition of smoke does not appear to be altered materially.
- Subjects :
- Nicotine
Chromatography, Gas
Mouth breathing
Acetaldehyde
Toxicology
Dogs
Phenols
Smoke
Respiration
Methods
medicine
Animals
Environmental Chemistry
Cigarette smoke
Acrolein
General Environmental Science
Carbon Monoxide
Inhalation
Chemistry
Smoking
Public Health, Environmental and Occupational Health
Water
Environmental Exposure
Environmental exposure
Carbon Dioxide
Tars
medicine.anatomical_structure
Equipment and Supplies
Anesthesia
Breathing
medicine.symptom
Chickens
Respiratory tract
Subjects
Details
- ISSN :
- 00039896
- Volume :
- 27
- Database :
- OpenAIRE
- Journal :
- Archives of Environmental Health: An International Journal
- Accession number :
- edsair.doi.dedup.....806c8c7caa320432cae7665a976ba3d8