Back to Search
Start Over
Enhanced West Nile Virus Surveillance in a Dengue-Endemic Area—Puerto Rico, 2007
Enhanced West Nile Virus Surveillance in a Dengue-Endemic Area—Puerto Rico, 2007
- Publication Year :
- 2013
- Publisher :
- The American Society of Tropical Medicine and Hygiene, 2013.
-
Abstract
- In June of 2007, West Nile virus (WNV) was detected in sentinel chickens and blood donors in Puerto Rico, where dengue virus (DENV) is hyperendemic. Enhanced human surveillance for acute febrile illness (AFI) began in eastern Puerto Rico on July 1, 2007. Healthcare providers submitted specimens from AFI cases for WNV and DENV virology and serology testing. Over 6 months, 385 specimens were received from 282 cases; 115 (41%) specimens were DENV laboratory-positive, 86 (31%) specimens were laboratory-indeterminate, and 32 (11%) specimens were laboratory-negative for WNV and DENV. One WNV infection was detected by anti-WNV immunoglobulin M (IgM) antibody and confirmed by a plaque reduction neutralization test. DENV and WNV infections could not be differentiated in 27 cases (10%). During a period of active WNV transmission, enhanced human surveillance identified one case of symptomatic WNV infection. Improved diagnostic methods are needed to allow differentiation of WNV and DENV in dengue-endemic regions.
- Subjects :
- Adult
Male
Endemic Diseases
West Nile virus
animal diseases
viruses
Dengue virus
medicine.disease_cause
Antibodies, Viral
Dengue fever
Serology
Dengue
Young Adult
Plaque reduction neutralization test
Neutralization Tests
Virology
medicine
Humans
biology
Transmission (medicine)
Puerto Rico
virus diseases
Articles
Dengue Virus
medicine.disease
nervous system diseases
Infectious Diseases
Immunoglobulin M
biology.protein
Parasitology
Female
Antibody
Sentinel Surveillance
West Nile Fever
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....80711d4424ee8c25d62da1de1cf80aac