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Triple visual hemifield maps in optic chiasm hypoplasia
Triple visual hemifield maps in optic chiasm hypoplasia
- Publication Year :
- 2019
- Publisher :
- Cold Spring Harbor Laboratory, 2019.
-
Abstract
- In humans, each hemisphere comprises an overlay of two visuotopic maps of the contralateral visual field, one from each eye. Is the capacity of the visual cortex limited to these two maps or are plastic mechanisms available to host more maps? Using an integrative approach of submillimeter fMRI, diffusion-weighted imaging and population receptive field mapping, we found three hemiretinal inputs to converge onto the left hemisphere in a rare individual with chiasma hypoplasia. This generates extremely atypical responses in striate and extrastriate cortices, specifically an overlay of three hemifield representations. Unexpectedly, the effects of this large abnormality on visual function in daily life are not easily detected. We conclude that developmental plasticity including the re-wiring of local intra- and cortico-cortical connections is pivotal to support the coexistence and functioning of three hemifield maps within one hemisphere.
- Subjects :
- education.field_of_study
genetic structures
Population
Optic chiasm
Biology
medicine.disease
Hypoplasia
Lateralization of brain function
030218 nuclear medicine & medical imaging
Visual field
03 medical and health sciences
0302 clinical medicine
Visual cortex
medicine.anatomical_structure
Receptive field
medicine
Developmental plasticity
education
Neuroscience
030217 neurology & neurosurgery
Subjects
Details
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....8081e2576931d94478115255801dec19
- Full Text :
- https://doi.org/10.1101/703520