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Progressive bronchial obstruction associated with toxic epidermal necrolysis

Authors :
Minoru Inage
Makoto Sata
Osamu Minamihaba
Shigeo Kondo
Hitonobu Tomoike
Hidenori Nakamura
Masanori Shirakabe
Yukie Osada
Hideki Tanida
Source :
Respirology (Carlton, Vic.). 4(1)
Publication Year :
1999

Abstract

Toxic epidermal necrolysis (TEN) is an acute life-threatening condition, characterized by erosion of the mucous membranes, extensive detachment of the epidermis, and severe constitutional symptoms. Pulmonary complications of TEN are reported as rare, but are one of the most common causes of death. Our report focuses on an unusual case of toxic epidermal necrolysis which showed multiple bronchial obliteration during the chronic phase of the disease. Biopsied tissue of the obliterated bronchi demonstrated non-specific granulation. To improve the obliterated ventilatory function, we tried to reopen the bronchial obliteration using a balloon catheter under the guidance of fibreoptic bronchoscopy, however rapid restenosis of the bronchi ensued.

Details

ISSN :
13237799
Volume :
4
Issue :
1
Database :
OpenAIRE
Journal :
Respirology (Carlton, Vic.)
Accession number :
edsair.doi.dedup.....809e94b07753d2dd9d9f468720cd3f4e