Supplemental Figure 2 from Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity

Effect of herbacetin on activity of various kinases. Herbacetin has no effect on (A) CHK1, (B) EGFR, (C) GSK3beta, (D) JNK1, (E) JNK2, (F) ERK1, (G) ERK2, (H) MEK1, (I) AKT1, (J) AKT2, (K) RSK2, (L) p38 or (M) PI3-K kinase activity or on (N) AdoMetDC activity. The effect of herbacetin on kinase or enzyme activity was determined by using an in vitro kinase or enzyme assay. All data are represented as mean values {plus minus} S.D. of values from duplicates experiments.