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Three-dimensional stereotactic surface projection study of orthostatic hypotension and brain perfusion image in Parkinson's disease

Authors :
Tamotsu Kubori
Hideaki Matsui
Takafumi Miyoshi
Masaya Oda
Fukashi Udaka
Kazuto Nishinaka
N. Hara
A. Tamura
Masakuni Kameyama
Source :
Acta Neurologica Scandinavica. 112:36-41
Publication Year :
2005
Publisher :
Hindawi Limited, 2005.

Abstract

Objective – To compare brain perfusion image using three-dimensional stereotactic surface projection (3D-SSP) analysis of N-isopropyl-p-123I iodoamphetamine (123I-IMP) single photon emission computed tomography (SPECT) between patients with Parkinson's disease with orthostatic hypotension and those without orthostatic hypotension. Materials and methods – Fifteen patients with Parkinson's disease and orthostatic hypotension and 13 patients with Parkinson's disease without orthostatic hypotension were studied. We compared brain perfusion image between the two groups by 3D-SSP. Results – Bilateral anterior cingulate gyrus perfusion of the patients with orthostatic hypotension was significantly decreased compared to that of the patients without orthostatic hypotension. Conclusions – The disorder of anterior cingulate gyrus may participate in the autonomic failure in Parkinson's disease.

Details

ISSN :
16000404 and 00016314
Volume :
112
Database :
OpenAIRE
Journal :
Acta Neurologica Scandinavica
Accession number :
edsair.doi.dedup.....8118bed5e8a88800df8ecf02006d44d7