Back to Search
Start Over
Developments in Treatment Methodologies Using Dendrimers for Infectious Diseases
- Source :
- Molecules, Vol 26, Iss 3304, p 3304 (2021), Molecules
- Publication Year :
- 2021
- Publisher :
- MDPI AG, 2021.
-
Abstract
- Dendrimers comprise a specific group of macromolecules, which combine structural properties of both single molecules and long expanded polymers. The three-dimensional form of dendrimers and the extensive possibilities for use of additional substrates for their construction creates a multivalent potential and a wide possibility for medical, diagnostic and environmental purposes. Depending on their composition and structure, dendrimers have been of interest in many fields of science, ranging from chemistry, biotechnology to biochemical applications. These compounds have found wide application from the production of catalysts for their use as antibacterial, antifungal and antiviral agents. Of particular interest are peptide dendrimers as a medium for transport of therapeutic substances: synthetic vaccines against parasites, bacteria and viruses, contrast agents used in MRI, antibodies and genetic material. This review focuses on the description of the current classes of dendrimers, the methodology for their synthesis and briefly drawbacks of their properties and their use as potential therapies against infectious diseases.
- Subjects :
- Polymers
Contrast Media
Pharmaceutical Science
Organic chemistry
HIV Infections
Review
02 engineering and technology
infectious diseases
01 natural sciences
antimicrobial therapy
Analytical Chemistry
dendrimers
Mice
Drug Delivery Systems
QD241-441
Anti-Infective Agents
Drug Discovery
antiviral therapy
diagnostics
Nanotechnology
Infectious Disease Medicine
Chemistry
Antiviral therapy
Stereoisomerism
Bacterial Infections
021001 nanoscience & nanotechnology
Magnetic Resonance Imaging
Virus Diseases
Chemistry (miscellaneous)
Drug delivery
Molecular Medicine
0210 nano-technology
Biotechnology
Antifungal
Coronavirus disease 2019 (COVID-19)
Anti-HIV Agents
medicine.drug_class
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Polypropylenes
010402 general chemistry
Communicable Diseases
Catalysis
Dendrimer
medicine
Animals
Humans
Physical and Theoretical Chemistry
SARS-CoV-2
COVID-19 Drug Treatment
0104 chemical sciences
Tomography x ray computed
Drug Design
drug delivery
nanoparticles
Peptides
Tomography, X-Ray Computed
Subjects
Details
- Language :
- English
- ISSN :
- 14203049
- Volume :
- 26
- Issue :
- 3304
- Database :
- OpenAIRE
- Journal :
- Molecules
- Accession number :
- edsair.doi.dedup.....815cbd074d853f06789ffbe33dda4bdc