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Ultimobranchial Body Remnants (Solid Cell Nests) as a Pitfall in Thyroid Pathology
- Source :
- The Journal of Clinical Endocrinology & Metabolism. 97:2209-2210
- Publication Year :
- 2012
- Publisher :
- The Endocrine Society, 2012.
-
Abstract
- We report the history of a pitfall in thyroid histopathology of a 47-yr-old man with a euthyroid nodular goiter involving the right lobe. The ultrasound-guided fineneedle aspiration of the dominant (3 cm) nodule, showing benign-appearing follicular cells, colloid, and scattered Hurthle cells, was consistent with a benign hyperplastic nodule (1). Because the left lobe had not shown evidence of nodular disease, the patient was submitted to a right lobectomy. The pathologist described a heavy lymphoplasmacyticbackgroundwithoccasionalgerminalcenter formation, as observed in Hashimoto thyroiditis, and a microscopic ( 1cm) follicularproliferationofepithelial thyroidcellswhose nucleidisplayedmembrane irregularityandchromatinclearing with occasional grooves. Thus, a histological report of a follicular variant of papillary microcarcinoma was issued. The patient underwent a completion thyroidectomy at the Federico II UniversityofNaples.At thatoccasion, thecompletesetofslides from both surgeries was reviewed by expert pathologists in the field of thyroid disease.
- Subjects :
- Male
endocrine system
medicine.medical_specialty
Pathology
Neoplasm, Residual
Goiter
endocrine system diseases
Endocrinology, Diabetes and Metabolism
Clinical Biochemistry
Hashimoto Disease
Ultimobranchial Body
Biochemistry
Diagnosis, Differential
Endocrinology
Internal medicine
Ultimopharyngeal body
medicine
Animals
Humans
Euthyroid
Thyroid Neoplasms
Thyroid cancer
Completion thyroidectomy
Pathology, Clinical
business.industry
Thyroid disease
Carcinoma
Biochemistry (medical)
Thyroid
Middle Aged
medicine.disease
Carcinoma, Papillary
medicine.anatomical_structure
Research Design
Thyroid Cancer, Papillary
Thyroidectomy
Histopathology
business
Subjects
Details
- ISSN :
- 19457197 and 0021972X
- Volume :
- 97
- Database :
- OpenAIRE
- Journal :
- The Journal of Clinical Endocrinology & Metabolism
- Accession number :
- edsair.doi.dedup.....81ee6d639dc6a3370504f9c4fa837cb8