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Effect of Methimazole Therapy on Thyroid Pathohistology That May Mimic Thyroid Malignancy

Effect of Methimazole Therapy on Thyroid Pathohistology That May Mimic Thyroid Malignancy

Authors :
Mirko Kontić
Valdi Pešutić Pisac
Hrvoje Punda
Ana Barić
Zaviša Čolović
Ante Punda
Source :
Acta Clinica Croatica, Acta Clinica Croatica, Vol 59., Iss Supplement 1, Pp 146-148 (2020)
Publication Year :
2020
Publisher :
Sestre Milosrdnice University Hospital and Institute of Clinical Medical Research, Vinogradska cesta c. 29 Zagreb, 2020.

Abstract

SUMMARY Diffuse toxic goiter, as the most common cause of hyperthyroidism, is usually initially treated with thyrostatic drugs such as methimazole, followed by radioiodine therapy or surgery which may be indicated as definitive treatment. Radioactive iodine therapy has a known association with various histopathologic features including cytologic atypia, but herein we present a rare example of morphological thyrocyte changes induced by long-term pharmacological treatment with methimazole that mimicked thyroid malignancy in a pathohistological sample.

Details

Language :
English
ISSN :
13339451 and 03539466
Volume :
59
Issue :
Suppl 1
Database :
OpenAIRE
Journal :
Acta Clinica Croatica
Accession number :
edsair.doi.dedup.....821a2ee4d2dd0745c59f8ec60e528d3d