HYPERLIPOPROTEINEMIA IN PATIENTS WITH CHRONIC RENAL FAILURE

Authors :: Morten Brøns
N. C. Christensen
Mogens Hørder
Source :: Brøns, M, Christensen, N C & Hørder, M 1972, ' HYPERLIPOPROTEINEMIA IN PATIENTS WITH CHRONIC RENAL FAILURE ', ACTA MEDICA SCANDINAVICA, vol. 192, no. 1-6, pp. 119-123 . https://doi.org/10.1111/j.0954-6820.1972.tb04787.x
Publication Year :: 2009
Publisher :: Wiley, 2009.
Abstract: Concentrations of triglycerides and cholesterol in serum and the distribution of plasma lipoprotein fractions have been studied in 25 patients with chronic non‐nephrotic renal failure. Hyperlipoproteinemia was demonstrated in 17 of them (type II 1 case, type III 1 case, type IV 13 cases, type V 2 cases). None of the recognized causes of secondary hyperlipoproteinemia appeared to be responsible for this high incidence. In 19 patients the i.v. glucose tolerance test showed abnormal responses. For patients with 24‐hour urinary losses of protein exceeding 3.5 g a statistically significant (inter‐patient) correlation was found between the concentration of triglyceride in serum and the rate of renal protein excretion. Including patients with milder degrees of proteinuria this relationship was obscured, and no further correlation could be established between serum lipid values and proteinuria, renal function or glucose tolerance. 1972 Association for the Publication of the Journal of Internal Medicine