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Pitfalls in estimation of glycosylated hemoglobin: A rare hemoglobin variant—Hb Hope
- Source :
- Journal of Diabetology, Vol 12, Iss 3, Pp 368-370 (2021)
- Publication Year :
- 2021
- Publisher :
- Medknow, 2021.
-
Abstract
- Hemoglobin (Hb) Hope is a rare Hb variant which is clinically silent but causes spuriously high glycated hemoglobin (HbA1c). We report a case of a 45-year-old gentleman, planned for elective total hip replacement, who presented with very high HbA1c with normal blood glucose and fructosamine levels. With the suspicion of erroneous HbA1c, an Hb electrophoresis was done, and he was found to have a rare hemoglobin variant called Hb Hope. We also reviewed almost all case reports of Hb Hope variant causing spuriously high HbA1c levels from India.
- Subjects :
- medicine.medical_specialty
endocrine system diseases
business.industry
Fructosamine levels
Total hip replacement
nutritional and metabolic diseases
Hemoglobin variants
RC648-665
glycosylated hb
Diseases of the endocrine glands. Clinical endocrinology
hb hope
Hba1c level
chemistry.chemical_compound
Endocrinology
chemistry
Internal medicine
Glycosylated hemoglobin A
medicine
hemoglobin variants
General Earth and Planetary Sciences
Glycated hemoglobin
Hemoglobin
Normal blood glucose
business
General Environmental Science
Subjects
Details
- ISSN :
- 20787685
- Volume :
- 12
- Database :
- OpenAIRE
- Journal :
- Journal of Diabetology
- Accession number :
- edsair.doi.dedup.....8275804f7f31665ca8a50e87bfafbbdc