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The effect of a dietary portfolio compared to a DASH-type diet on blood pressure
- Source :
- Nutrition, metabolism, and cardiovascular diseases : NMCD. 25(12)
- Publication Year :
- 2015
-
Abstract
- Background and aim Compared to a DASH-type diet, an intensively applied dietary portfolio reduced diastolic blood pressure at 24 weeks as a secondary outcome in a previous study. Due to the importance of strategies to reduce blood pressure, we performed an exploratory analysis pooling data from intensively and routinely applied portfolio treatments from the same study to assess the effect over time on systolic, diastolic and mean arterial pressure (MAP), and the relation to sodium (Na + ), potassium (K + ), and portfolio components. Methods and results 241 participants with hyperlipidemia, from four academic centers across Canada were randomized and completed either a DASH-type diet (control n = 82) or a dietary portfolio that included, soy protein, viscous fibers and nuts (n = 159) for 24 weeks. Fasting measures and 7-day food records were obtained at weeks 0, 12 and 24, with 24-h urines at weeks 0 and 24. The dietary portfolio reduced systolic, diastolic and mean arterial blood pressure compared to the control by 2.1 mm Hg (95% CI, 4.2 to −0.1 mm Hg) (p = 0.056), 1.8 mm Hg (CI, 3.2 to 0.4 mm Hg) (p = 0.013) and 1.9 mm Hg (CI, 3.4 to 0.4 mm Hg) (p = 0.015), respectively. Blood pressure reductions were small at 12 weeks and only reached significance at 24 weeks. Nuts, soy and viscous fiber all related negatively to change in mean arterial pressure (ρ = −0.15 to −0.17, p ≤ 0.016) as did urinary potassium (ρ = −0.25, p = 0.001), while the Na + /K + ratio was positively associated (ρ = 0.20, p = 0.010). Conclusions Consumption of a cholesterol-lowering dietary portfolio also decreased blood pressure by comparison with a healthy DASH-type diet. Clinical Trial Reg. No. NCT00438425, clinicaltrials.gov.
- Subjects :
- Adult
Male
medicine.medical_specialty
Mean arterial pressure
Canada
Mediterranean diet
Endocrinology, Diabetes and Metabolism
Diastole
Medicine (miscellaneous)
Hyperlipidemias
Diet, Mediterranean
Diet Records
Risk Assessment
Plant protein
Animal science
Internal medicine
Hyperlipidemia
medicine
Humans
Diet, Fat-Restricted
Aged
Nutrition and Dietetics
business.industry
Sodium
Coronary heart disease risk
Blood Pressure Determination
Diet, Sodium-Restricted
Middle Aged
Cardiovascular disease
medicine.disease
3. Good health
Blood pressure
Endocrinology
Treatment Outcome
Cardiovascular Diseases
Decreased blood pressure
Hypertension
Female
Cardiology and Cardiovascular Medicine
business
Energy Intake
Vegetable protein
Follow-Up Studies
Subjects
Details
- ISSN :
- 15903729
- Volume :
- 25
- Issue :
- 12
- Database :
- OpenAIRE
- Journal :
- Nutrition, metabolism, and cardiovascular diseases : NMCD
- Accession number :
- edsair.doi.dedup.....828b4522fa2c5493fbe55e8f7a571847