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The effect of a dietary portfolio compared to a DASH-type diet on blood pressure

Authors :
Jiri Frohlich
C. Pellini
Robert G. Josse
Balachandran Bashyam
Patrick Couture
Christopher Ireland
Lawrence A. Leiter
R. J. de Souza
Benoît Lamarche
Arash Mirrahimi
P. Galange
Cyril W. C. Kendall
Vanu Ramprasath
Viranda H. Jayalath
John L. Sievenpiper
Dorothea Faulkner
Peter B. Jones
L. S. A. Augustin
David J.A. Jenkins
Korbua Srichaikul
Stephanie K. Nishi
Source :
Nutrition, metabolism, and cardiovascular diseases : NMCD. 25(12)
Publication Year :
2015

Abstract

Background and aim Compared to a DASH-type diet, an intensively applied dietary portfolio reduced diastolic blood pressure at 24 weeks as a secondary outcome in a previous study. Due to the importance of strategies to reduce blood pressure, we performed an exploratory analysis pooling data from intensively and routinely applied portfolio treatments from the same study to assess the effect over time on systolic, diastolic and mean arterial pressure (MAP), and the relation to sodium (Na + ), potassium (K + ), and portfolio components. Methods and results 241 participants with hyperlipidemia, from four academic centers across Canada were randomized and completed either a DASH-type diet (control n = 82) or a dietary portfolio that included, soy protein, viscous fibers and nuts (n = 159) for 24 weeks. Fasting measures and 7-day food records were obtained at weeks 0, 12 and 24, with 24-h urines at weeks 0 and 24. The dietary portfolio reduced systolic, diastolic and mean arterial blood pressure compared to the control by 2.1 mm Hg (95% CI, 4.2 to −0.1 mm Hg) (p = 0.056), 1.8 mm Hg (CI, 3.2 to 0.4 mm Hg) (p = 0.013) and 1.9 mm Hg (CI, 3.4 to 0.4 mm Hg) (p = 0.015), respectively. Blood pressure reductions were small at 12 weeks and only reached significance at 24 weeks. Nuts, soy and viscous fiber all related negatively to change in mean arterial pressure (ρ = −0.15 to −0.17, p ≤ 0.016) as did urinary potassium (ρ = −0.25, p = 0.001), while the Na + /K + ratio was positively associated (ρ = 0.20, p = 0.010). Conclusions Consumption of a cholesterol-lowering dietary portfolio also decreased blood pressure by comparison with a healthy DASH-type diet. Clinical Trial Reg. No. NCT00438425, clinicaltrials.gov.

Details

ISSN :
15903729
Volume :
25
Issue :
12
Database :
OpenAIRE
Journal :
Nutrition, metabolism, and cardiovascular diseases : NMCD
Accession number :
edsair.doi.dedup.....828b4522fa2c5493fbe55e8f7a571847