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Identification of exocytotic membrane proteins, syntaxin-1 and SNAP-25, in Entamoeba histolytica from hamster liver
- Source :
- Hepatology Research. 37:473-476
- Publication Year :
- 2007
- Publisher :
- Wiley, 2007.
-
Abstract
- Entamoeba histolytica is a protozoan parasite causing dysentery and in some cases liver abscesses. These effects have been attributed to cytolytic substances released by exocytosis. In this study, the presence of the proteins syntaxin-1 and SNAP-25, which are assumed to be involved in exocytosis, were examined by immunohistochemistry, immunoelectron microscopy and western blot analysis. Syntaxin-1 and SNAP-25 were expressed in the vesicular, vacuolar and plasma membranes of E. histolytica trophozoites. It can be concluded that these proteins might be involved in exocytosis processes.
- Subjects :
- food.ingredient
Hepatology
biology
medicine.diagnostic_test
Immunoelectron microscopy
Hamster
biology.organism_classification
Syntaxin 1
Molecular biology
Exocytosis
Cell biology
Amoeba (genus)
Entamoeba histolytica
Infectious Diseases
food
nervous system
Western blot
Membrane protein
parasitic diseases
medicine
Subjects
Details
- ISSN :
- 1872034X and 13866346
- Volume :
- 37
- Database :
- OpenAIRE
- Journal :
- Hepatology Research
- Accession number :
- edsair.doi.dedup.....82e3f026431d9bbeba83c59a3c8213bd