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A Comparison Between the HeRO Graft and Conventional Arteriovenous Grafts in Hemodialysis Patients
- Source :
- Seminars in Dialysis. 27:310-318
- Publication Year :
- 2014
- Publisher :
- Wiley, 2014.
-
Abstract
- Venous stenosis and occlusion are a major cause of vascular access dysfunction and failure. The HeRO Graft bypasses occlusion and traverses stenosis with outflow directly into the central venous circulation. A randomized, multicenter study was conducted to evaluate the efficacy and safety of the HeRO Graft relative to conventional AV grafts. The design was to enroll 143 patients in a 2:1 randomization ratio between HeRO and conventional AV control groups. Data on 72 subjects (52 HeRO Graft and 20 AV graft controls) were obtained. The HeRO Graft and control cohorts were comparable in baseline characteristics. Adequacy of dialysis, bacteremia rates, and adverse events were consistent between groups. Twelve month Kaplan-Meier estimates for primary and secondary patency rates were 34.8% and 67.6% in the HeRO Graft cohort, and 30.6% and 58.4% in the control cohort. There was no statistical difference in terms of patency between groups. The rates of intervention were 2.2/year for HeRO Graft and 1.6/year for the control (p = 0.100). Median days to loss of secondary patency was 238 for HeRO Graft versus 102 for the control (p = 0.032). The HeRO Graft appears to provide similar patency, adequacy of dialysis, and bacteremia rates to those of conventional AV grafts.
- Subjects :
- Adult
Male
medicine.medical_specialty
medicine.medical_treatment
Prosthesis Design
Upper Extremity
Young Adult
Arteriovenous Shunt, Surgical
Blood vessel prosthesis
Occlusion
medicine
Humans
HERO
Vascular Patency
Dialysis
Aged
business.industry
Graft Occlusion, Vascular
Middle Aged
Vascular surgery
medicine.disease
Blood Vessel Prosthesis
Surgery
Stenosis
surgical procedures, operative
Nephrology
Cohort
Kidney Failure, Chronic
Female
Hemodialysis
business
Subjects
Details
- ISSN :
- 08940959
- Volume :
- 27
- Database :
- OpenAIRE
- Journal :
- Seminars in Dialysis
- Accession number :
- edsair.doi.dedup.....82fa297b540ce2cfcf9e22c26aba2c07